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Amanda Welin

Docent and associated clinical WCMM fellow with a focus on optimized laboratory diagnostics

Novel clinical applications of imaging flow cytometry

My group's research aims to solve clinical problems through improved laboratory diagnostics. We use imaging flow cytometry - a technique combining flow cytometry and fluorescence microscopy - as our main tool, enabling quantitative morphological analysis of thousands of cells in flow. The technique is applied to blood samples from different patient groups where there is a clinical need for faster, more objective diagnostics or detailed information about cell populations and their interactions.

I'm a resident physician in clinical chemistry at Region Östergötland and since 2015 associate professor in medical microbiology. In my doctoral work I studied mycobacterial survival mechanisms inside innate immune cells. After defending my thesis at LiU in 2011, I did a postdoc at the Sahlgrenska Academy focusing on human neutrophil subpopulations, followed by a postdoc at the University of Zürich funded by the Swedish Research Council, where I used an amoeba model to study intracellular bacterial infections. In 2019 I returned to Linköping University as a principal investigator, in recent years combined with clinical work, and I was appointed an associated clinical WCMM fellow in 2025.

Publications

2025

Srikanth Mairpady Shambat, Puran Chen, Rocky M Barilla, Markus Huemer, Johanna Snäll, Amanda Welin, Taylor S Cohen, Virginia Takahashi, Samuel B Berry, Alejandro Gómez-Mejia, Tiziano A Schweizer, Danen M Cunoosamy, Sara Cajander, Magda Lourda, Volkan Özenci, Ewerton Marques Maggio, Reto A Schüpbach, Kristoffer Strålin, Annelies S Zinkernagel, Anna Norrby-Teglund, Mattias Svensson (2025) mBio, p. e0268925-, Article e0268925 (Article in journal)

2023

Amanda Welin, Dario Hüsler, Hubert Hilbi (2023) Spectral and Imaging Cytometry: Methods and Protocols, p. 63-85 (Chapter in book)
Hans Lundquist, Henrik Andersson, Michelle S Chew, Jyotirmoy Das, Maria V Turkina, Amanda Welin (2023) Journal of Innate Immunity, Vol. 15, p. 351-364 (Article in journal)
Vignesh Venkatakrishnan, Jonas Elmwall, Trisha Lahiri, Martina Sundqvist, Linda Bergqvist, Hakon Leffler, Ulf J. Nilsson, Amanda Welin, Johan Bylund, Anna Karlsson-Bengtsson (2023) Glycobiology, Vol. 33, p. 503-511 (Article in journal)
Martina Sundqvist, Karin Christenson, Per Wekell, Halla Bjornsdottir, Agnes Dahlstrand Rudin, Felix P. Sanchez Klose, Tilmann Kallinich, Amanda Welin, Lena Bjorkman, Johan Bylund, Anna Karlsson-Bengtsson, Stefan Berg (2023) Frontiers in Immunology, Vol. 14, Article 1233101 (Article in journal)

Organisation