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Division of Molecular Medicine and Virology (MMV)

At the Division of Molecular Medicine and Virology our research focus is on the understanding how different factors and signaling pathway regulate cells and tissue development and to understand how different viruses infect and affect cellular functions and our immune system.

The research involves studies on the molecular biology level as well as studies of biological effects on cells, on tissue, and organisms. The aim and goal with the research is to gain new knowledge and use it to to find new ways to prevent, diagnose and cure disease.

The division is involved in medical and biomedical education programs, both at undergraduate and Master’s level, as well as in education of PhD-students and post-doctoral fellows. The aim is to provide the students a knowledge and interest to continue with research within our research fields.


Research

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Wallenberg Centre for Molecular Medicine at LiU

WCMM at LiU focuses on the medicine-technology interface, and build upon our existing strengths in research within medical technology, materials science and bioengineering.

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Tumor Immunology and Immunotherapy

The aims of our research are to uncover the cellular and molecular mechanisms that predispose to systemic and long-term anti-tumor immunity and the mechanisms that drive resistance to immunotherapy.

Top image for the Lottersberger lab.

Genome integrity: from nuclear structure to telomere protection

We study the molecular mechanisms that preserve genome stability in mammalian cells and their roles in cancer and ageing.

News

The shape of the cell nucleus influences cancer treatment

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA, shows a new study. The results may also explain why combining certain cancer drugs can produce the opposite of the intended effect.

Chevalier Barley.

Protection against winter vomiting bug spread with arrival of agriculture

A genetic variant that protects against stomach virus infections appeared when humans began farming. This is shown by researchers at LiU and Karolinska Institutet, after analysing the genomes of 4,300 ancient individuals and cultivated “mini-guts”.

Female researcher working with cells in a lab.

New discovery reveals how chromosome ends can be protected

Researchers have uncovered a previously unknown mechanism that safeguards the chromosome ends from being mistakenly repaired by the cell - a mistake with potentially catastrophic outcomes.

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